Exploring Diabetes Clinical Trials in California for February 2026

3 minute read

By Shawn Hayes

California stands as a pivotal center for diabetes clinical trials, offering a wealth of opportunities for individuals eager to participate in transformative research. These trials, spanning both Type 1 and Type 2 diabetes, aim to pioneer new treatments and enhance management strategies. Discover the diverse trials available and their potential to revolutionize diabetes care and improve health outcomes.

Exploring Diabetes Clinical Trials in California

California is a hub for diabetes clinical trials, offering numerous opportunities for individuals to participate in groundbreaking research. With a focus on both Type 1 and Type 2 diabetes, these trials aim to explore new treatments, improve management strategies, and enhance the quality of life for those affected by diabetes. The University of California Health system, for instance, is actively conducting 118 diabetes clinical trials, with 60 trials currently open for eligible participants. These trials cover various aspects of diabetes management and treatment, providing a platform for cutting-edge research (source).

Key Trials and Their Focus Areas

Among the notable trials is the VX-880 trial, which is focused on participants with Type 1 Diabetes (T1D) and impaired awareness of hypoglycemia. This study evaluates the safety, tolerability, and efficacy of VX-880 infusion, with eligibility for individuals aged 18-65. Conducted in San Francisco and other locations, it aims to address severe hypoglycemia in this population (source).

Another significant trial is the Dulaglutide (LY2189265) trial, targeting pediatric participants with Type 2 Diabetes Mellitus, aged 10-17. This study aims to evaluate additional dosing options for dulaglutide over an 8-month period, with locations in San Francisco and beyond (source).

The GNTI-122 trial is a Phase 1 study for adults recently diagnosed with T1D, aged 18-45. It assesses the safety and efficacy of GNTI-122, an investigational cell therapy, over a 78-week period. The trial includes multiple cohorts and is conducted in San Francisco and other locations (source).

Innovative Approaches and Future Directions

In addition to these trials, the RO7446603 study investigates the safety and efficacy of treatments for diabetic macular edema (DME) in participants aged 18 and up. The study includes both Phase I and Phase II segments, with trials taking place in San Francisco and other locations (source).

The DECIDE trial is a comparative effectiveness study of metformin versus insulin for gestational diabetes treatment. It involves 1,572 pregnant individuals across 20 U.S. sites, including San Francisco, and follows participants through delivery and two years postpartum (source).

Furthermore, the DREAM project focuses on improving diabetes device usage among Latinx adolescents with T1D in California. It involves a virtual peer group intervention to support device use and aims to evaluate clinical and person-centered outcomes (source).

Why You Should Learn More About Diabetes Clinical Trials in California Today

Participating in diabetes clinical trials in California offers individuals the chance to contribute to vital research that could transform diabetes treatment and management. These trials not only provide access to new therapies and interventions but also help advance scientific understanding of diabetes. With a wide range of trials available, from those focusing on pediatric Type 2 diabetes to innovative cell therapies for Type 1 diabetes, there are numerous opportunities for eligible participants to get involved. By engaging in these trials, individuals can play a crucial role in shaping the future of diabetes care and potentially improve their own health outcomes.

Contributor

Shawn is a dedicated health and wellness writer, bringing a wealth of experience in nutritional coaching and holistic living. He is passionate about empowering readers to make informed choices about their physical and mental well-being. Outside of writing, Shawn enjoys hiking, mountain biking, and exploring new recipes to share with friends and family.